Optimal control for chemotherapy scheduling

Start: 09/28/2015 - 4:00pm
End  : 09/28/2015 - 5:00pm

Applied Math Seminar

Minaya Villasana (Universidad Simón Bolívar)


In this talk some advances on the optimal control model formulation and resolution for chemotherapy scheduling is presented.  Firstly, a DDE model is introduced for tumor progression with immune response upon which a suitable optimal control problem formulation is devised and several heuristic algorithms are evaluated.  A second model that incorporates two drugs: cytotoxic and cytostatic is presented.  We show numerically that the optimal scheduling on this new model corresponds to an asynchronous delivery. 

Emmy Noether Room, Millikan 1021, Pomona College