Modeling drug kinetics in slow-release tablets: mathematical approaches and challenges

Start: 01/25/2012 - 1:15pm
End  : 01/25/2012 - 2:15pm

Applied Math Seminar

Ami Radunskaya, Pomona College


Many drugs are most effective when their concentration in the blood is maintained at a fixed level. To obtain this concentration profile, pharmacists must create sustained-release tablets that deliver the drug as slowly as possible without waste. Matrix tablets made up of drug and polymer are a cost-effective solution, but a theoretical basis for the prediction of release curves is needed. In this talk we will describe several approaches to this problem, and describe some of the questions that still remain.

This work is in collaboration with Peter Hinow (U. of Wisconsin, Milwaukee).

RN 103